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Hypnotic-sedatives and anxiolytics

They are a group of psychotropic drugs used to treat insomnia and anxiety, mainly. The first sedative sedative was synthesized in 1864 and was barbituric acid.






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The effects of barbiturates are very similar to those of alcohol, presenting cross-dependence with said substance, that is, they partially or totally suppress the symptoms of physical dependence.

The main risk of consuming barbiturates is that tolerance occurs quickly, however, despite increasing the dose, the lethal dose threshold does not go back, so it is very easy to die from an overdose. In addition to this, physical and psychological dependence on this substance is quickly created and its withdrawal syndrome can be very dangerous, so it requires hospital admission since delirium tremens, epileptoid crisis, and sometimes becomes fatal. The serious withdrawal syndrome, the rapid tolerance, their addictive power and the risk of being able to be used as autolytic instruments caused them to be withdrawn from the market in the sixties. Parallel to this, in the fifties benzodiazepines began to be used, which little by little displaced the use of barbiturates since they implied fewer side effects, however in the sixties the first evidence of the addictive power of some benzodiazepines appeared like Valium.


In most cases, the consumption of these substances is started by prescription, however their inappropriate use leads to dependence; at present it lights the health alarms for its abusive use among consumers of other substances such as heroin who use it by mixing them with alcohol to achieve some of the effects of the substance.


Normal Effects:

  • They improve the mood

  • Reduce anxiety

  • They promote states of relaxation and induce sleep.

In high doses:

  • Difficulties in psychomotor coordination.

  • Confusion and lightheadedness.

  • Sickness.

  • Slowness in the association of ideas.

Symptoms of withdrawal syndrome:

  • Anxiety.

  • Tremors

  • Sickness.

  • Irritability.

  • Muscle tension.

  • Anorexy.

  • Insomnia.

  • Depression.

Their effects increase when combined with alcohol or other central nervous system depressants and the risk of death from cardiorespiratory arrest is increased since the functioning of the central nervous system is dangerously diminished.


  • Do not consume without a prescription

  • Do not consume recreationally

  • Do not mix with alcohol or other substances

  • If consumed by medical prescription: follow the dosage instructions and follow the gradual reduction instructions when the treatment is finished, in order to manage the symptoms of physical dependence effectively.

General recommendations for the consumption of psychoactive substances:

📌Do not consume any psychoactive substance, if you do so other than on a regular basis.

📌 Take care of yourself physically before, during and after consumption through nutrition and hydration.

📌Implement detoxification strategies the days after consumption

🔥 Warning signs 🔥

If you feel the need to increase the dose to feel the effects you initially felt, give yourself a break and do not consume for a long time, this will decrease tolerance, keep it there through non-habitual consumption, that is, do not take part of your routine or that the consumption does not present a pattern.

💡Do you want to detox? At # deliberate we have designed a DETOX program at home: 7 days with nutritional advice, physical activity, recipes (breakfast, lunch and dinner), mindfulness exercises, imagery exercises and steam baths; Give your body a detoxification day once every six months and avoid negative consequences for your health in the medium and long term. More info here 💡Do you want to manage your consumption? Book an appointment with our healthcare professionals. Find out whether or not you have a problem use and acquire strategies to reduce risks and harm from using psychoactive substances. More info here

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